Accuracy of single progesterone assay to predict early pregnancy outcome

Dr. K Vandana; Dr. Dasharatha Murmu; Dr. Harika Mathi

Volume : VII, Issue : VI, June - 2018

Accuracy of single progesterone assay to predict early pregnancy outcome

Dr. K Vandana, Dr. Dasharatha Murmu, Dr. Harika Mathi

Abstract :

OBJECTIVE: To study the accuracy of estimation of single serum progesterone level in predicting early pregnancy outcome in symptomatic women with inconclusive USG

MATERIAL AND METHODS: 70 women with gestational age less than 12 weeks fulfilling the inclusion criteria were included in the study.

RESULTS: Out of 70 women, the follow up scan revealed 33 viable pregnancies and 37 non–viable pregnancies. Mean serum progesterone was significantly higher in viable pregnancy group (16.318� 7.29 ng/ml), compared with non–viable pregnancy group (8.07� 5.878ng/ml) and the association was found to be statistically significant with a �p� value of 0.0001.Serum progesterone of 10ng/ml has sensitivity of 72.97% in predicting a non–viable pregnancy and specificity of 81.81% in predicting viable pregnancy.

CONCLUSION: Single serum progesterone value of less than 10ng/ml can be a useful test in predicting early pregnancy failure in symptomatic patients with inconclusive USG.