Volume : VI, Issue : VII, July - 2017
A STUDY ON FINE NEEDLE ASPIRATION CYTOLOGY WITH POST OPERATIVE HISTOPATHOLOGY CORRELATION OF LUMP BREAST
Dr Sathyamoorthy Karuppiah, Dr Thiruppathy Chakkaravarthy, Dr Selvamuthukumaran Gunasekaran
Abstract :
BACKGROUND
A method of definitive diagnosis of patients who present with palpable east lump at the outpatient clinic is needed now a days. This method must be accurate, easy to perform and acceptable to the patient, can be carried out in a busy clinic setting and must not require too much preparation or expensive equipment. This study was conducted to compare the diagnostic accuracy of fine needle aspiration cytology(FNAC) in differentiating the benign and malignant lesions of palpable east lump with histopathological correlation .
Methodology
One year prospective study from June 2015 to July 2016 involving 75 cases of women presenting in Surgery outpatient department, Government Dharmapuri Medical College Hospital with complaints of lump east. Patients underwent FNAC of the palpable east lump after thorough physical examination. The cytological report was described as benign, suspicious and malignant. Patient was informed about the report and proceeded with lumpectomy or mastectomy and histopathological confirmation. Later diagnostic accuracy of cytology reporting was compared with that of histopathology.
Results
FNAC had a diagnostic accuracy of 100% for patient with benign east lesions and 93.55% for malignant east lesions. The sensitivity of FNAC in diagnosing patients presenting with lump in east was 100%.The specificity was 93.55%. The positive predictive value of 95.65%. The negative predictive value for FNAC was 100%.
K–coefficient–– 1.001068 which implies FNAC as a screening test and its results are comparable with the gold standard histopathological examination.
Conclusion
The FINE NEEDLE ASPIRATION CYTOLOGY (FNAC) is an essential and important test in diagnosing and managing patient presenting with lump east. It is patient friendly, easy to perform, more reliable, repeatable and a simple test to diagnose patient presenting with lump east. The accuracy of diagnosis increase if FNAC is performed and slides smeared and reported by an expert. High sensitivity and high positive predictive value shows that a patient with positive FNAC means a definite and accurate diagnosis of the concerned pathology when compared with the final histopathology report. The high specificity and a high negative predictive value of FNAC for malignancy showed the high accuracy of FNAC in the diagnosing malignancy. Thus, we conclude that FNAC is an important and essential preliminary test in diagnosing a patient presenting with east lump and proceed with appropriate surgical management and it shows high degree of correlation with the final histopathological report. From our results, it can be advised that the patients in which FNAC is unequivocally diagnostic for cancer can be managed directly by mastectomy or any other definitive therapy
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DOI : 10.36106/ijsr
Cite This Article:
DR SATHYAMOORTHY KARUPPIAH, DR THIRUPPATHY CHAKKARAVARTHY, DR SELVAMUTHUKUMARAN GUNASEKARAN, A STUDY ON FINE NEEDLE ASPIRATION CYTOLOGY WITH POST OPERATIVE HISTOPATHOLOGY CORRELATION OF LUMP BREAST, INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : VOLUME-6 | ISSUE-7 | JULY-2017
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DR SATHYAMOORTHY KARUPPIAH, DR THIRUPPATHY CHAKKARAVARTHY, DR SELVAMUTHUKUMARAN GUNASEKARAN, A STUDY ON FINE NEEDLE ASPIRATION CYTOLOGY WITH POST OPERATIVE HISTOPATHOLOGY CORRELATION OF LUMP BREAST, INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : VOLUME-6 | ISSUE-7 | JULY-2017
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