A Study of Oxidative Stress and Antioxidant  Defense in Subjects with Metabolic Syndrome

Dr. Pratibha Chauhan; Dr. Girdharee Lal Saini

Volume : II, Issue : XII, December - 2013

A Study of Oxidative Stress and Antioxidant Defense in Subjects with Metabolic Syndrome

Dr. Pratibha Chauhan, Dr. Girdharee Lal Saini

Abstract :

Aims & Objectives:- To evaluate the role of oxidative stress and antioxidant status in metabolic syndrome. Materials and methods:- This is a hospital based study carried out by simple random sampling technique in the general population in 18 to 60 years age group irrespective of their gender status. A pretested question was used for recording the information of each subject and their educational status, religion, physical activity, type of diet and substance abuse were enquired. Venous blood samples of each subject were taken and biochemical analysis was done in fully automated analyzer and semi-auto analyzer. Statistical analysis of the data was done using �Z� test and two-way ANOVA. Results:- In the study, 24.6% of the subjects had Metabolic syndrome. Oxidative stress was highest in subjects with Metabolic Syndrome (MetS) and Antioxidant vitamin status of the subjects with MetS statistically lowered with increase in number of risk factors. Conclusion:- This type of study helps in the identification of risk factors in MetS subjects so that preventive measures can be taken.