Volume : VII, Issue : X, October - 2018
A STUDY OF ETIOLOGY AND CLINICAL PROFILE OF PANCYTOPENIA IN ADULTS
Divakar Kumar, Malyaban Das, Vidyapati, Prajit Mazumdar, Chandramani Kumar
Abstract :
Background: Pancytopenia is a relatively common hematological entity. It is a striking feature of many serious and life threatening illnesses. The severity of pancytopenia and the underlying pathology determine the management & prognosis. Thus identification of etiology will help for better management and complete cure and better treatment of patients.
Objectives:
1. To find out the underlying etiopathology of pancytopenia.
2. To study the clinical presentations in pancytopenia due to various causes.
Methods: This study was a cross sectional study that was conducted at department of medicine of Rajendra Institute of medical sciences on one hundred pancytopenia patients who were evaluated clinically, along with hematological parameters and bone marrow aspiration.
Results: Among 100 cases studied ,most patients presented with generalized weakness. The commonest physical finding was pallor followed by splenomegaly and hepatomegaly. Macrocytic anaemia was the predominant blood picture.. The commonest bone marrow finding wasmegaloblastic erythroid hyperplasia. The commonest cause for pancytopenia was megaloblastic anemia (60%), followed by haematological malignancy (20%) and aplastic anemia (12%). Other causes of pancytopenia were hypersplenism, leishmaniasis.
Conclusion: The commonest cause of pancytopenia in our study is megaloblastic anemia. This is in sharp contrast to the commonest cause of pancytopenia in various studies throughout the world where aplastic anemia has been the most common cause.
Keywords :
Article:
Download PDF
DOI : 10.36106/ijsr
Cite This Article:
Divakar Kumar, Malyaban Das, Vidyapati, Prajit Mazumdar, Chandramani Kumar, A STUDY OF ETIOLOGY AND CLINICAL PROFILE OF PANCYTOPENIA IN ADULTS, INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-7 | Issue-10 | October-2018
Number of Downloads : 196
References :
Divakar Kumar, Malyaban Das, Vidyapati, Prajit Mazumdar, Chandramani Kumar, A STUDY OF ETIOLOGY AND CLINICAL PROFILE OF PANCYTOPENIA IN ADULTS, INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-7 | Issue-10 | October-2018
Our Other Journals...
-
Indian Journal of
Applied Research Visit Website -
PARIPEX Indian Journal
of Research Visit Website -
Global Journal for
Research Analysis Visit Website