Volume : IX, Issue : IV, April - 2020
A Randomized, Double-Blinded,Controlled Study For Comparative Evaluation Of Intrathecal Administration Of Levobupivacaine With Fentanyl And Levobupivacaine
Geetha Ramadurai, Shobhit Singh, Neelam Singh, L. S. Mishra, Krishna Chandra Gupta
Abstract :
Context:Intrathecal administration of levobupivacaine with fentanyl and levobupivacaine with magnesium sulfate for postoperative analgesia.Aim:To compare the quality and duration of postoperative analgesia by addition of fentanyl or magnesium sulfate to levobupivacaine given intrathecally.Setting and design: The study was conducted as a Randomized, Double–Blinded, Controlled Study in a 1200 bedded teaching hospital.Materials and methods:60 patients undergoing lower abdominal surgery were randomly divided into two groups 30 each, group LF received 12.5 mg of 0.5% isobaric levobupivacaine with 25mcg fentanyl. Group LM received 12.5 mg of 0.5% isobaric levobupivacaine with 25mg of magnesium sulfate. Onset of sensory and motor block, duration and quality of analgesia was noted along with intraoperative hemodynamic parameters.Statistical analysis: Microsoft Excel 2010 with student ‘t’ test (unpaired) and one way ANOVA were used for compå the two groups.Results:The addition of fentanyl to levobupivacaine prolonged the duration of sensory block(LF 235.83±18.10 vs LM 205.17±19.14),motor block(LF 190.5±13.60 vs LM 152.47±10.63) and duration of analgesia(LF 287.5±16.12 vs LM 246.33±19.38) compared to MgSO4 with p<0.05 found statistically significant.Conclusion:Intrathecal levobupivacaine plus fentanyl prolonged the duration of sensory and motor block and provided prolonged duration of analgesia.
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DOI : 10.36106/ijsr
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A RANDOMIZED, DOUBLE-BLINDED,CONTROLLED STUDY FOR COMPARATIVE EVALUATION OF INTRATHECAL ADMINISTRATION OF LEVOBUPIVACAINE WITH FENTANYL AND LEVOBUPIVACAINE, Geetha Ramadurai, Shobhit Singh, Neelam Singh, L.S. Mishra, Krishna Chandra Gupta INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-9 | Issue-4 | April-2020
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A RANDOMIZED, DOUBLE-BLINDED,CONTROLLED STUDY FOR COMPARATIVE EVALUATION OF INTRATHECAL ADMINISTRATION OF LEVOBUPIVACAINE WITH FENTANYL AND LEVOBUPIVACAINE, Geetha Ramadurai, Shobhit Singh, Neelam Singh, L.S. Mishra, Krishna Chandra Gupta INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-9 | Issue-4 | April-2020
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