A Randomized Controlled Double Blind  Study to Compare Dexmedetomidine 5 �g  and 10 �g as an Adjuvant to Intrathecal  Bupivacaine

Dr. Keshav Govind Rao; Dr Manoj Kumar Chaurasiya; Dr Pawan Kapoor; Dr Aparna Shukla

Volume : II, Issue : XII, December - 2013

A Randomized Controlled Double Blind Study to Compare Dexmedetomidine 5 �g and 10 �g as an Adjuvant to Intrathecal Bupivacaine

Dr. Keshav Govind Rao, Dr Manoj Kumar Chaurasiya, Dr Pawan Kapoor, Dr Aparna Shukla

Abstract :

Objective- This study was designed to compare the effect of two doses of dexmedetomidine [5mcg and 10 mcg] on onset and duration of sensory and motor block of hyperbaric bupivacaine when given intrathecally. Methods- Study was conducted in 52 ASA I/II patients posted for lower abdominal surgeries under subarachnoid block. Patients were divided in two groups of 26 patients each. Group 1 and group 2patients received 5mcg and 10 mcg dexmedetomidine respectively with 12.5 mg bupivacaine heavy intrathecally. Onset and duration of sensory and motor block was assessed. Result- Dexmedetomidine reduced onset and prolonged the duration of sensory and motor block of hyperbaric bupivacaine .No significant side effect or haemodynamic instability noted in either group. Conclusion- Dexmedetomidine is good alternative as an adjuvant to intrathecal bupivacaine in surgical procedures that require long time with minimal side effects.