A Brief Review on Rational Consideration of Fixed Dose Combinations.

Dr. Satish Chandel; Dr. Abhay Joshi; Dr. Rakesh Sonawane; Dr. Nidhi Jain

Volume : III, Issue : VI, June - 2014

A Brief Review on Rational Consideration of Fixed Dose Combinations.

Dr. Satish Chandel, Dr. Abhay Joshi, Dr. Rakesh Sonawane, Dr. Nidhi Jain

Abstract :

The irrational prescription of fixed dose combinations is a major health concern in our country. The Indian pharmaceutical market is flooded with fixed dose combinations. The production and sale of these products are increasing day by day. Few of such products have ethical and rational basis. Fixed dose combinations enhance the efficacy of product, decrease the chances of drug resistance and improve patient compliance. On the other hand, there are some disadvantages associated like, difficulty in dose adjustment of individual drug, complexity of dose rating, irrational prescription, ineffective and unsafe treatment, exacerbation or prolongation of illness, and higher treatment cost. The awareness regarding merits, demerits and rational aspect of fixed dose combinations among the physicians is very essential to prevent irrational prescribing practices. We have tried to consolidate important aspects of fixed dose combination with hope to improve awareness regarding this issue.