TUMOUR CLEARANCE IN ADVANCED OVARIAN CANCER WITH AND WITHOUT NEO ADJUVANT CHEMOTHERAPY

Chitra Devi Vinayagam; Vijayalakshmi Elumalai

Volume : VI, Issue : XII, December - 2016

TUMOUR CLEARANCE IN ADVANCED OVARIAN CANCER WITH AND WITHOUT NEO ADJUVANT CHEMOTHERAPY

Chitra Devi Vinayagam, Vijayalakshmi Elumalai

Abstract :

Ovarian malignancies are one of the most common gynecological malignancies in India next to uterine malignancies presenting very late in advanced stages accounting for 7% of all cancer diagnosis.Life time risk of ovarian carcinoma is 1.9%.Most common of these ovarian tumors are the epithelial cancers described as silent killers because overwhelming majority of these don‘t present with any of these symptoms except vague abdominal discomfort and bloating sensation.Tumor markers like ca125 elevated only in advanced stages and more it is like a prognostic indicator only.Neoadjuvant chemotherapy was introduced in the year 1969 for patients with advanced ovarian cancer who were medically unfit .Later neoadjuvant chemotherapy was extended to all severe stages of ovarian malignancy to achieve better survival rate after surgery.Aim of this study is to identify tumour clearance effect of neoadjuvant chemotherapy in advanced ovarian tumour and to compare it with those who have not received neoadjuvant chemotherapy(NACT).