To Study the Relationship Between Various Functional Outcome And Neuro–Imaging in Acute Ischemic Strokes

Dr CS Mohanty; Dr Anuj Singhal; Dr Sougat Ray

Volume : VI, Issue : X, October - 2016

To Study the Relationship Between Various Functional Outcome And Neuro–Imaging in Acute Ischemic Strokes

Dr Cs Mohanty, Dr Anuj Singhal, Dr Sougat Ray

Abstract :

Introduction A more than one third of stroke survivors are left with permanent disability in the form of significant residual physical, cognitive and psychological impairments. Accurate outcome prediction following stroke is important for the proper delivery of post stroke care and establishment of an effective continuing care program. In this study we have tried to find out the relationship between various functional outcome and neuroimaging in acute ischemic strokes. Methodology Study was conducted at a tertiary care centre in over a period of 1 years. Patients detected to have acute stoke were evaluated at enrolment (within 7 days from stroke onset) and during follow up at 12 weeks after stroke by the same observer. All the patients were given standard care as per the guidelines of American Stroke Association. Primary outcome was to assess the functional outcome in acute ischemic stroke at the end of 12 weeks and to study the correlation between the functional outcome scales and findings on neuroimaging of ain. Results Sixty nine patients were screened for the study and 58 patients met the eligibility criteria. Out of 58 patients, 8 patients had presented within window period (3h – 4 1/2 h). The overall mortality during 12 weeks amounted to 10.3% and was higher in men (6.9%) than women (3.4%). Infarct size and BI score at admission, 4 weeks and at 12 weeks were found to be negatively correlated (p<0.001) which means that as the infarct size increased, BI score decreased. Similarly, infarct size and MRS score at admission and at follow up was positively correlated Patient (p<0.001). Stroke with smaller (<3 cm3) infarct size had better outcome than larger infarct (>3 cm3) i.e 44.4% vs 3.7% using BI (BI>90) and 94.4% vs 55 % using MRS score (MRS ≤3). Conclusion The infarct size and BI score at admission and at follow up was negatively correlated and infarct size and MRS score at admission and at follow up was positively correlated. The functional outcome of the anterior circulation stroke was better as compared to the posterior circulation stroke. All the modifiable risk factors except Type 2 Diabetes Mellitus had adverse impact in the functional outcome.