The parkinsons disease sleep scale: evaluation of sleep disturbances in Parkinsons disease patients

Justin C; Manivannan M R; Shakthi C

Volume : IX, Issue : III, March - 2019

The parkinsons disease sleep scale: evaluation of sleep disturbances in Parkinsons disease patients

Justin C, Manivannan M R, Shakthi C

Abstract :

Introduction: The pathology of parkinsons disease extends far beyond the nigrostriatal dopamine pathway and results in non motor symptoms in addition to the commonly accepted motor symptoms. The most common being autonomic dysfunction, mood disorders, and sleep problems. Sleep disturbances occur in 96% of patients with parkinson’s disease and appear to arise from a combination of neurochemical and neurodegenerative process involving central sleep regulatory centres such as foreain ,thalamus and midain dopamine neurons. We evaluated sleep symptoms in parkinson’s disease patients which are one of the predominant non motor manifestations impairing quality living. Methods : We enrolled 103 patients with Parkinsons disease in our study and were given PDSS questionnaire addressing 15 items includes overall quality of night’s sleep, sleep onset, nocturnal restlessness, nocturnal psychosis, nocturia, nocturnal motor symptoms, sleep refreshment, daytime sleepiness. Results: PDSS were impaired in advanced stages more than early stages. Conclusion: Sleep disturbance in parkinsons disease especially daytime sleepiness is associated with vehicle accidents and impairs the quality of life. PDSS can be used as screening tool to subject patients to sleep studies and aiming at treating them.