Volume : VII, Issue : VI, June - 2017

The association between clinical parameters and retinal nerve fiber layer thickness in patients with multiple sclerosis

Semra Mungan, Mualla Hamurcu, Nese Oztekin, Isil Guzel, Gurdal Orhan

Abstract :

 Multiple sclerosis (MS) is an autoimmune disorder characterized by demyelinization, inflammation, axonal/neuronal loss and gliosis of white matter of central nervous system (CNS) with multifactorial etiology including genetic, environmental and immunological factors [1]. Optic neuritis is a common pathology that may affect nearly half of the patients with MS and also may lead to thinning of the retinal nerve fiber layer (RNFL) due to the neuroinflammation of the optic nerve (2). Spain et al (3) reported that RNLF measured by optical coherence tomography (OCT) may be correlated with disease duration and EDSS scores in patients with untreated MS. In another study RNLF was found to discriminate patients with sub types of MS including clinically isolated syndrome patients; relapsing remitting MS patients; secondary progressive MS (4). 

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Semra Mungan, Mualla Hamurcu, Nese Oztekin, Isil Guzel, Gurdal Orhan, The association between clinical parameters and retinal nerve fiber layer thickness in patients with multiple sclerosis, INDIAN JOURNAL OF APPLIED RESEARCH : Volume‾7 | Issue‾6 | June‾2017

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