SYSTEMIC LUPUS ERYTHEMATOSUS. Molecular basis of disease Part 2

Eliseo Ruiz Bedolla; Briceida Lopez Martinez; Israel Parra Ortega

Volume : IX, Issue : VIII, August - 2019

SYSTEMIC LUPUS ERYTHEMATOSUS. Molecular basis of disease Part 2

Eliseo Ruiz Bedolla, Briceida Lopez Martinez, Israel Parra Ortega

Abstract :

The exact etiology of lupus erythematosus still is unknown. The genetic factors play an important role in the predisposition of the disease however some environmental factors are required to trigger the disease. Has been observed some relation among the activity of enzyme acetyltransferase and the presence of SLE; also has been found some disorders in structure of collagen during disease, so as changes of enzymes activity in blood and changes on levels of amino acids in blood and urine of patients with SLE. Among these amino acids are arginine, ornithine, proline and hydroxyproline. On the other hand also has been found non–protein amino acids on blood samples of patients with SLE and they are considered as triggers of SLE.