Study to Evaluate the Role of Single Intrapleural Steroid  Instillation in Improving Outcome in Patients of Tubercular  Pleural Effusions Receiving Standard Anti Tubercular  Treatment

Dr Gauri Paresh Godbole; Dr Amolkumar Diwan; Dr. Himanshu Pophale; Dr. Samir Singru

Volume : III, Issue : X, October - 2013

Study to Evaluate the Role of Single Intrapleural Steroid Instillation in Improving Outcome in Patients of Tubercular Pleural Effusions Receiving Standard Anti Tubercular Treatment

Dr Gauri Paresh Godbole, Dr Amolkumar Diwan, Dr. Himanshu Pophale, Dr. Samir Singru

Abstract :

The pleural inflammatory reaction in TB results in long term restricted lung function after the standard ATT in a significant proportion of observed cases. Research findings about benefit of use of oral corticosteroids are inconsistent. There is only one study on intrapleural corticosteroid instillation. 114 adult patients with simple tuberculous pleural effusions received single intrapleural hydrocortisone succinate 100 mg dose with standard ATT. Their outcome was compared with a control group of 120 patients receiving standard ATT, in terms of improvement in CXR, USG, dyspnoea scores and spirometry at the end of 2 and 6 months. The study group showed statistically significant improvement in all these outcome parameters as compared with the control group.