Volume : X, Issue : V, May - 2020

Study of Clinico Hematological correlation of Patients with chronic myeloid leukemia (CML)

Dr Kalpana Nayak, Dr Deepak Kumar

Abstract :

Introduction: Chronic myeloid leukemia is a slowly progressing type of blood cell cancer that begins in bone marrow. Chronic myeloid leukemia typically affects older adults. It is caused by a chromosome mutation that occurs spontaneously. Chronic myeloid leukemia (CML) is a myeloproliferative disorder characterized by a reciprocal translocation between chromosomes 9 and 22. Chronic Myeloid Leukemia (CML) is a disorder of proliferation which is unrestrained and excessive maturation proceeds fairly normally. The disease occurs chiefly between the ages of 30 and 80 years with a peak of 55 years. The main objective was to study the Clinico hematological correlation of patients with chronic myeloid leukemia. Method: The study was conducted on 50 patients in LTBRKM Hospital Jagdalpur Chhattisgarh. The study was conducted for a period of 3 year from 2016 – 2019. All patients with a diagnosis of Leukemia were assessed. Permission from institutional ethical committee was taken. Patients between 17 – 75 years were included. Clinical examination includes full history and physical examination, blood examination. Result: of 50 patients 5 were between age 15–20 years,12patients were between age 21–30 years, 15 patients are between age 31 – 40 years, 7 patients were between age 41–50 years.3 patients are between age 51– 60 years and 8 patients are between age 61–75 years. Out of 50 patients, 36 were males and 14 were females. Conclusion: The most common treatment method is chemotherapy. Bone marrow transplants, radiation are also available options. Chemotherapy is the most preferred method for treatment of leukemia

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Article: Download PDF    DOI : 10.36106/ijar  

Cite This Article:

STUDY OF CLINICO HEMATOLOGICAL CORRELATION OF PATIENTS WITH CHRONIC MYELOID LEUKEMIA (CML), Dr Kalpana Nayak, Dr Deepak Kumar INDIAN JOURNAL OF APPLIED RESEARCH : Volume-10 | Issue-5 | May-2020

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