STUDY OF CLINICAL AND LABORATORY PROFILE IN MALARIA

Dr Himanshu Sekhar Dash; Dr Smita Padhy

Volume : V, Issue : XII, December - 2015

STUDY OF CLINICAL AND LABORATORY PROFILE IN MALARIA

Dr Himanshu Sekhar Dash, Dr Smita Padhy

Abstract :

Background and Objectives: Malaria is a major health problem in many parts of India . Several factors have been attributed to increased morbidity and mortality in malaria with altered haematological and coagulation parameters playing an important role. Material and Methods: 50 patients of Malaria confirmed by PS, MPQBC or Antigen Assay underwent detailed clinical history, thorough physical examination and investigated with haematological, required routine and special investigations. This was followed by monitoring the outcome of the patients with respect to morbidity and mortality. Results: Of the 50 patients 8 patients had severe anaemia (Hb% <6gm %) and all of these patients were falciparum and mixed infection cases. Thrombocytopenia was observed in 60% of the patients and severe thrombocytopenia (<50,000 cumm) was seen in 5% of the patients. PT and APTT were increased in 22% and 11% of the cases respectively. BT was increased in 5% of the cases. 1 patients in the study expired. Conclusion: Severe Anaemia is a poor prognostic factor and has adverse outcome. Increased BT is associated with high mortality. Mixed infection behaves like falciparum malaria.