Volume : IX, Issue : VII, July - 2019

STUDY OF ASSOCIATION BETWEEN VITAMIN D3 AND PSORIASIS.

Dr. Sadan Khan, Dr. L. G Abichandani

Abstract :

Background: Psoriasis is a common, chronic, disfiguring, inflammatory and proliferative condition of the skin. The epidermal layer of skin on exposure to sun by the action of UVB, via a photochemical reaction, the B ring of 7–dehydrocholesterol is oken to form pre–vitamin D3 or cholecalciferol, which is subsequently converted first to 25–hydroxyvitamin D (25OHD) and then to 1, 25–hydroxyvitamin D (1, 25(OH) D or calcitriol) the active form of vitamin D. Aim and Objectives: To analyse the serum level of, Vitamin D3.To compare & correlate serum levels of, Vitamin D3 in cases of psoriasis and in same patients under treatment after time period of 6 month. Material and Methods: 30 freshly diagnosed patients of psoriasis were included in the study. Results: Paired t–test was statistically significant. Conclusion: Damage to epithelial layer affects vitamin d synthesis, evidence is accumulating that vitamin D represents a key modulator of immune and inflammation mechanisms. Both these mechanism have cumulative effect in exacerbation epidermal damage in skin lesions results in proper vitamin D synthesis which also supplements skin healing immunologically for skin lesion

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

STUDY OF ASSOCIATION BETWEEN VITAMIN D3 AND PSORIASIS., Dr. Sadan Khan, Dr. L. G Abichandani INDIAN JOURNAL OF APPLIED RESEARCH : Volume-9 | Issue-7 | July-2019

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