Role of various modifiable factors and drugs in the treatment of isolated systolic hypertension in elderly population.

Sana Rehman; Razi Ahmad; Zenis Baluja; Anwar Habib

Volume : VII, Issue : VII, July - 2017

Role of various modifiable factors and drugs in the treatment of isolated systolic hypertension in elderly population.

Sana Rehman, Razi Ahmad, Zenis Baluja, Anwar Habib

Abstract :

Prevalence and severity of hypertension are strongly associated with the advancing age, women have lower systolic blood pressure as compare to men during early adulthood, however after menopause blood pressure increases in women to levels even higher than in men. In elderly population isolated systolic hypertension is a major health problem predisposing them to substantially increased risk for stroke, coronary artery disease and congestive heart failure. Adequate control of systolic blood pressure by life style modification and appropriate use of medicine can improve the quality of life and productivity in this population. The aim of the present study was to evaluate the effect of various modifiable factors and appropriate drug /drugs that is most suitable for controlling systolic blood pressure in elderly population. This was a retrospective observational study conducted on the patients attending medicine department of Hakeem Abdul Hameed Centenary Hospital, Delhi. Elderly hypertensive were included in the study. The prevalence of ISH in the study population was found to be 63.18 %, among of them men and women were 31.81% and 31.36%. Angiotensin receptor blockers were found to be the most appropriate drug in single drug regimen, whereas calcium channel blocker in combination with beta blocker produced best result in two drug combination therapy and calcium channel blocker plus ARB and hydrochlorothiazide provided best result where more than two drug was used. In our study various modifiable factors were strongly related to the development of ISH whereas only 6.36% study population were having family history of hypertension which suggest that hypertension and isolated systolic hypertension, both can be controlled with minor modification in our routine lifestyle.