Volume : IX, Issue : VIII, August - 2019

ROLE OF TOPICAL PLATELET RICH PLASMA IN MANAGEMENT OF CHRONIC ULCERS

Mahalakshmi Ashok Kumar, Yeganathan Rajappan, Manimaran Thangavelu, Rajeswari Appanamuthu Mari

Abstract :

INTRODUCTION: Wound healing depends on various factors such as on. Platelet derived growth factors(PDGF) are biologically active substances that serve as messengers to regulate a well orchestrated and complex series of events involving cell to cell and cell to matrix interactions.( 1)And so Therefore Local application of PDGF that stimulate wound repair was an appealing proportion. The purpose of this prospective randomized study was to investigate the efficacy and safety of topical platelet rich plasma in management of patients with chronic ulcers(2). MATERIALS AND METHODS : Patients enrolled by simple randomization to participate in study and divided in to two groups. Group A with platelet rich plasma dressing and Group B with regular normal saline dressing. Platelet rich plasma is prepared by double centrifugation method from whole blood. Platelet pellets are formed at the end of this method. Pellets along with plasma used for dressing. RESULTS: The wound was assessed before start of treatment and after 5th and 10th day of treatment. The size and epithelization were used to evaluate the healing process. CONCLUSION: Platelet rich plasma dressing helps in alliterated wounds contraction and early epitheration. without any hence platelet rich plasma dressing cani be used as an adjunct to conventional treatment.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

ROLE OF TOPICAL PLATELET RICH PLASMA IN MANAGEMENT OF CHRONIC ULCERS, Mahalakshmi Ashok kumar, Yeganathan Rajappan, Manimaran Thangavelu, Rajeswari Appanamuthu Mari INDIAN JOURNAL OF APPLIED RESEARCH : Volume-9 | Issue-8 | August-2019

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