Volume : VII, Issue : VI, June - 2017

Review Article on Granulation Process with Novel Technology: An overview

L. P. Patil, V. P. Rawal

Abstract :

 For making Compressed Tablet, it is necessary to prepare the material in a dry, granular form to render it suitable for passing through a compression machine. Granulation is one of the most important unit operations in the production of pharmaceutical oral dosage forms. Granulation, the process of particle enlargement by agglomeration technique, is one of the most significant unit operations in the production of pharmaceutical dosage forms, mostly tablets and capsules. Granulation process transforms fine powders into free–flowing, dust free granules that are easy to compress. Granulation process will improve flow and compression characteristics, reduce segregation, improve content uniformity, and eliminate excessive amounts of fine particles and also enhance the physical and chemical stability of the drug. High–shear wet granulation, fluidized–bed granulation, and roller compaction followed by milling are commonly used granulation techniques in the pharmaceutical industry. This review focuses on the recent progress in the granulation techniques and technologies such as pneumatic dry granulation reverse wet granulation, steam granulation, moisture–activated dry granulation, thermal adhesion granulation, freeze granulation, and foamed binder or foam granulation.

Keywords :

Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

L.P. PATIL, V.P. RAWAL, Review Article on Granulation Process with Novel Technology: An overview, INDIAN JOURNAL OF APPLIED RESEARCH : Volume‾7 | Issue‾6 | June‾2017

Number of Downloads : 2395

References :