Volume : V, Issue : V, May - 2015

Relation of obesity with total leucocyte count in metabolic syndrome

Dr . Nerella Sharvani, Ms Pagadala Pravallika, Mr. R. Nasar Ahamed

Abstract :

Considerable amount of interest has been focused on the positive relationship between inflammation  and the metabolic syndrome. However few studies have been performed to evaluate the relationship  between baseline total leucocyte count and future risk for developing metabolic syndrome. Therefore we assess the  relation of total leucocyte count ( TLC) with obesity in the patients of Metabolic Syndrome. Waist circumference, as a  criteria for obesity was used to compare the total leucocyte count in 50 controls and 50 patients aged 20 – 50 years.  TLC was determined using automated Coulter (Diatron) by venepuncture . In Comparison with the controls, TLC was  higher in patients and statistically significant difference (p<0.0001) was observed between the two groups. This finding  could be attributed to pro inflammatory cytokines (TNF–α and IL– 6) released from adipose cells, insulin resistance mediated increase in inflammatory markers, decrease in adiponectin and increase in leptin. Thus, TLC in obese patients of  Metabolic syndrome can be used as a predictor for future complications in them.

Keywords :

Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Dr .Nerella Sharvani, Ms Pagadala Pravallika, Mr. R. Nasar Ahamed Relation of obesity with total leucocyte count in metabolic syndrome Indian Journal of Applied Research, Vol.5, Issue : 5 May 2015

Number of Downloads : 677

References :