Prevalence and Drug Resistance Pattern Among Diabetic Pulmonary Tuberculosis Patients Treated Under RNTCP

Dr. Vikas Kumar Mishra; Dr. Neeraj Gour; Dr Suresh Kumar Jangir; Dr. Neeraj Gupta

Volume : VI, Issue : III, March - 2016

Prevalence and Drug Resistance Pattern Among Diabetic Pulmonary Tuberculosis Patients Treated Under RNTCP

Dr. Vikas Kumar Mishra, Dr. Neeraj Gour, Dr Suresh Kumar Jangir, Dr. Neeraj Gupta

Abstract :

INTRODUCTION: – Tuberculosis has been a major cause of suffering and death since time immemorial. Thought to be one of the oldest human diseases, the history of tuberculosis is at least as old as the mankind. People with diabetes have 2–3 times higher risk of TB compared to people without diabetes. About 10% of TB cases globally are linked to diabetes. Management of Tuberculosis becomes a bit difficult with diabetes as a comorbid condition as poor glycemic control. Hence therefore we have planned this study “Prevalence And Drug Resistance Pattern Among Diabetic Pulmonary Tuberculosis Patients Treated Under RNTCP”. AIMS and OBJECTIVES:– 1. Prevalence of Diabetes mellitus among Tuberculosis patients registered under RNTCP. 2. Drug sensitivity pattern among smear positive retreatment diabetic patients. MATERIALS AND METHODS: This study was conducted in The Department of Respiratory Medicine, JLN Medical College, Ajmer from 1st January 2012 to 31st December 2012. RESULTS: – Most of the patients were between 31 to 60 years (75.01%) and maximum (39.30%) in 41 to 50 years. There is an overall male predominance with male female ratio 2.1:1. The prevalence of diabetes mellitus among patients of tuberculosis was 7.356. Type–2 diabetes mellitus was present in 94.05% patients. In 75% patients were Rifampicin and Isoniazid resistant. In 75% patients Rifampicin and Isoniazid resistant were present in those in which HBA1c level was >8.0 and in 25% patients Rifampicin and Isoniazid sensitive in which HBA1c level was up to 7.0.