Volume : IV, Issue : X, October - 2014
Metalloproteinase (MMPs) As Prognostic and Diagnostic Tool in Periodontics–A Review
Dr. Bhoomika Khosya, Dr. Devaraj C. G. , Dr. Spiti Datta
Abstract :
Matrix Metalloproteinase (MMPs)are group of enzyme that in concert are responsible for the degradation of most extracellular matrix proteins during organogenesis,growth and normal tissue turnover. The expression and activity of MMPs in adult tissue is normally quite low, but increases significantly in various pathological condition that may lead into unwanted tissue destruction,such as in inflammatory disease,tumor growth and metastasis. MMPs have a marked role in tissue destructive oral disease.the role of collagenase,especially MMP–8 in periodontitis and peri–implantitis is the best known example of unwanted tissue destruction related to increased presence and activity of MMPs at site of disease.
Keywords :
Matrix metalloproteinase Periodontitis Tissue inhibitors of Matrix metalloproteinase (TIMPs) extracellular matrix (ECM).
Article:
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DOI : 10.36106/ijar
Cite This Article:
Dr. Bhoomika Khosya, Dr. Devaraj C.G., Dr.Spiti Datta Metalloproteinase (MMPs) As Prognostic and Diagnostic Tool in Periodontics � A Review Indian Journal of Applied Research, Vol.4, Issue : 10 October 2014
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Dr. Bhoomika Khosya, Dr. Devaraj C.G., Dr.Spiti Datta Metalloproteinase (MMPs) As Prognostic and Diagnostic Tool in Periodontics � A Review Indian Journal of Applied Research, Vol.4, Issue : 10 October 2014
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