Lipid Profile in Hemorrhagic Stroke – A Study From Government General Hospital / Siddhartha Medical College Vijayawada –Andhra Pradesh

DR. T. Sikindar Mohan; DR. R. Siddeswari

Volume : VII, Issue : IX, September - 2017

Lipid Profile in Hemorrhagic Stroke – A Study From Government General Hospital / Siddhartha Medical College Vijayawada –Andhra Pradesh

Dr. T. Sikindar Mohan, Dr. R. Siddeswari

Abstract :

Aim and objectives: To identify and describe lipid profile abnormalities in patients of hemorrhagic Stroke.

Materials and Methods

This is a retrospective descriptive study of 50 patients who were admitted in Government General Hospital Vijayawada during last two years with new onset hemorrhagic stroke. A detailed history physical examination and outcome details of patients were collected from the hospital medical records. Data such as fasting lipid profile, Computed Tomography (CT) or Magnetic resonance imaging (MRI) ain were collected from medical records and studied for lipid abnormalities associated with hemorrhagic stroke.

Results

A total of 50 patients were studied of whom 24 were males and females were26.Patients with age<50 years were n=10; age between 51– 60years n=21 between 61–70years n=12 and age above 71years n=7. Hypertension is the major risk factor n= 30 patients, patients diabetes n=12, both diabetics and hypertensive n=11. Most common sites of bleed was capsuloganglionic n= 42, other sites of bleeds include pons n= 2, basal ganglia n= 2, cerebellar n= 2, subarachnoid hemorrhage n= 2 . Dyslipedemia (defined as ratio of total to HDL cholesterol >4.5 in n= 37 of patients as per ICMR report. As per NCEP/ ATP III guidelines in the present study, patients with low HDL Cholesterol( <40mg/dl) were n=39(78%),high LDL(>130mg/dl) was found in n= 27(54%), high total Cholesterol( >200mg/dl) was found in n= 24(48%), ,high Triglycerides(>150mg/dl) n=12(24%)and elevated non HDL c (>130mg/dl) in n=28(56%). 15 patients (30%) were having 30–40% stenosis of internal carotid artery. Total number of deaths is n=4 (8%).

Conclusion– In the present study concludes the increasing age, hypertension, dyslipedemia, Low HDL, elevated LDL and Non HDL are associated with hemorrhagic strokes. As per Indian Council of Medical Research (ICMR)surveillance project report prevalence of dyslipedemia (defined as ratio of total cholesterol to HDL cholesterol >4.5)was in 37 patients .The present study concludes importance of early diagnosis and treatment of hypertension, lipid abnormalities and improving HDL levels by anerobic exercise, weight loss, smoking cessation.