Volume : VIII, Issue : V, May - 2018
Langerhans Cell Histiocytosis: Morphology and Immunohistochemistry still remain the important keys for diagnosis
Dr. Mona Bargotya, Dr. Ankita Mehta, Dr. Rajni Parmar, Dr. Tejinder Singh
Abstract :
Langerhans cell histiocytosis (LCH) is a rare clonal proliferation disorder of cells with phenotype of activated Langerhans cells. It encompasses a spectrum of diseases characterized by the proliferation and infiltration of organs by pathological Langerhans cells. It occurs mostly in children and young adults and involves one or more body systems. It may have a variable clinical course with remissions and relapses. It occurs mostly in children and young adults and involves one or more body systems such as bone, hypothalmus, posterior pitutary gland, lymph nodes, liver or various soft tissues. It is twice as frequent in males as compared to females, and can occur in all the ages. We conducted a retrospective study, in which all the diagnosed cases of LCH, from November 2016 to October 2017were selected. Clinical details, Hematoxylin and eosin (H & E)stained and immunohistochemistry (IHC) slides were retrieved from the records.
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DOI : 10.36106/ijar
Cite This Article:
Dr. Mona Bargotya, Dr. Ankita Mehta, Dr. Rajni Parmar, Dr. Tejinder Singh, Langerhans Cell Histiocytosis: Morphology and Immunohistochemistry still remain the important keys for diagnosis, INDIAN JOURNAL OF APPLIED RESEARCH : Volume-8 | Issue-5 | May-2018
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Dr. Mona Bargotya, Dr. Ankita Mehta, Dr. Rajni Parmar, Dr. Tejinder Singh, Langerhans Cell Histiocytosis: Morphology and Immunohistochemistry still remain the important keys for diagnosis, INDIAN JOURNAL OF APPLIED RESEARCH : Volume-8 | Issue-5 | May-2018
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