Volume : VI, Issue : VII, July - 2016
Incidence of Adverse Drug Reaction Among the Tuberculosis Patients Treated Under Directly Observed Treatment Short course (DOTS) Regimen in North India
Mohd. Khalid Hassan, Aboobacker Siddique. P. A, Rajendra Kumar Karadiya, Arindam Chakraborty
Abstract :
Objective: Adverse drug reactions (ADR) in anti–tuberculous drugs act as an important factor for treatment failure. The present observational study was undertaken to demonstrate the extent of adverse effects of anti–tuberculosis drug used in category 1st category 2nd and category 3rd, treatment regimens under DOTS and impact of these adverse drug reaction on the clinical outcome of treatment. Materials and Methods: A total of 196 patients between with tuberculosis (TB), who were treated under DOTS in category 1st, 2nd, and 3rd were included in the study. Two consecutive sputum smear examination and culture were performed for the diagnosis of pulmonary TB. Further investigation like X–ray chest PA view was also done for the confirmation of pulmonary TB. Result: Out of 196 patients 82(42%) were developed ADR. In females higher incidence (47.5%) of adverse drug reactions were observed. Among different categories the higher number of adverse drug reactions were observed in category 2. In all the categories the maximum numbers of incidence of ADR were noted in gastro intestinal tract (GIT) Conclusion: Female as well as patient with category two is more prone to develop ADR. So physician should take proper care while treating these patients to prevent gastrointestinal discomfort which is more common.
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DOI : 10.36106/ijar
Cite This Article:
Mohd. Khalid Hassan, Aboobacker Siddique. P.A, Rajendra Kumar Karadiya, Arindam Chakraborty Incidence of Adverse Drug Reaction Among the Tuberculosis Patients Treated Under Directly Observed Treatment Short course (DOTS) Regimen in North India Indian Journal of Applied Research,Volume : 6 | Issue : 7 | July 2016
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Mohd. Khalid Hassan, Aboobacker Siddique. P.A, Rajendra Kumar Karadiya, Arindam Chakraborty Incidence of Adverse Drug Reaction Among the Tuberculosis Patients Treated Under Directly Observed Treatment Short course (DOTS) Regimen in North India Indian Journal of Applied Research,Volume : 6 | Issue : 7 | July 2016
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