In vitro Anti-fungal Properties of Aqueous Extract of Wild Ganoderma sp from Nigeria

Shamaki; Bala Usman; Abdulrahman; Fanna Inna; Sandabe; Umar Kyari; Sa'idu; Shehu Na'Allah Alhaji; Tekdek; Lazarus Baba; Gulani; Isa Adamu

Volume : IX, Issue : III, March - 2019

In vitro Anti-fungal Properties of Aqueous Extract of Wild Ganoderma sp from Nigeria

Shamaki, Bala Usman, Abdulrahman, Fanna Inna, Sandabe, Umar Kyari, Sa Idu, Shehu Na Allah Alhaji, Tekdek, Lazarus Baba, Gulani, Isa Adamu

Abstract :

Investigation into the in vitro anti–fungal activities of aqueous extract of wild Ganoderma sp. from Lafia, Nassarawa State, Nigeria was conducted using disc diffusion technique. 100 mg/ml, 200 mg/ml, and 300 mg/ml reconstituted aqueous extract of the wild Ganoderma specie was tested against mixed fungal isolates from infected goats. These fungi are Dermatophilos congolensis, Rhyzopus oryzae, Aspergillus niger and Penicilium sp. Results showed that the anti–fungal activities were concentration dependent of 8 mm (100 mg/ml), 9 mm (200 mg/ml) and 11 mm (300 mg/ml) zone of inhibition of the mixed infection respectively. Although all preparations showed anti–fungal activity, only 300 mg/ml concentration have high anti–fungal activity with the zone of inhibition being 11 mm, 1 mm higher than the standard ≥ 10 mm required for an agent to be considered as possessing antimicrobial activity. This finding is relevant in discussing treatment of dermatological disease condition in goats caused by mixed fungal origin.