Volume : VI, Issue : IV, April - 2016
GRAM POSITIVE BACTERIAL PATHOGENS IN ACUTE EXACERBATION OF COPD AND ANTIBIOTIC SENSITIVITY PATTERN OF THESE ORGANISMS
V. Viswambhar, B. Sowjanya, N. Meenakshi, Dr Aruna Shanmuganathan, S. Subramanian, Vishnu Sharma. M
Abstract :
Introduction: Knowledge of common bacterial pathogens and their sensitivity pattern to antibiotics will help in early proper institution of appropriate antibiotic therapy in AECOPD. Materials and methods: Sputum culture and sensitivity was done in 90 patients admitted with AECOPD. Those patients with gram positive bacterial infection on sputum culture were analysed for antibiotic sensitivity pattern. Results: Gram positive organisms were isolated in 29 cases. Most common was streptococcus pneumoniae (45%), followed by streptococcus pyogenes (34%). 100% of Streptococcus pneumoniae were sensitive to 3rd generation cephalosporins (p=0.0001 CI 95) and Piperazillin+ Tazobactum, 89% were susceptible to Levofloxacin. 80% were susceptible to ciprofloxacin. Streptococcus pyogenes was susceptible for both Ciprofloxacin & Levofloxacin. Conclusions: The most common gram positive organism in our study causing AECOPD was streptococcus pneumoniae followed by streptococcus pyogenes. Initial emperical antibiotic therapy can be started with a 3rd generation cephalosporin or ciprofloxacin.
Keywords :
AECOPD Gram positive bacterial infections Antibiotic sensitivity pattern Empirical antibiotic therapy.
Article:
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DOI : 10.36106/ijar
Cite This Article:
V.Viswambhar, B.Sowjanya, N.Meenakshi, Dr Aruna Shanmuganathan, S.Subramanian, Vishnu Sharma.M GRAM POSITIVE BACTERIAL PATHOGENS IN ACUTE EXACERBATION OF COPD AND ANTIBIOTIC SENSITIVITY PATTERN OF THESE ORGANISMS Indian Journal of Applied Research, Vol.6, Issue : 3 March 2016
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V.Viswambhar, B.Sowjanya, N.Meenakshi, Dr Aruna Shanmuganathan, S.Subramanian, Vishnu Sharma.M GRAM POSITIVE BACTERIAL PATHOGENS IN ACUTE EXACERBATION OF COPD AND ANTIBIOTIC SENSITIVITY PATTERN OF THESE ORGANISMS Indian Journal of Applied Research, Vol.6, Issue : 3 March 2016
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