Evaluation of TG/HDL Cholesterol ratio and non HDL/HDL ratio as a marker of Cardiovascular risk in Diabetics Mellitus

Sunita D. Singh; Nita Garg

Volume : VIII, Issue : X, October - 2018

Evaluation of TG/HDL Cholesterol ratio and non HDL/HDL ratio as a marker of Cardiovascular risk in Diabetics Mellitus

Sunita D. Singh, Nita Garg

Abstract :

Aim: The aim of our study was to determine lipid profile levels in diabetics and nondiabetics and to evaluate cardiovascular risk using TG/HDLc ratio and Non HDLc/HDLc ratios.

Study Design:A hospital based cross sectional study was conducted on patients attending the Out Patient Department of Medicine of Doon Medical College, Dehradun (Uttarakhand) during a period of 06 months from January 2018 to June 2018.200 patients (100 Diabetics + 100 Non–diabetics) in the age group 30–80 years were selected randomly for the study.Of the 100 Diabetics (52 Male + 48 Female) and of the 100 Non diabetics 56 were males and 44 were females. All the participants underwent biochemical analysis–FBS, PPBS, HbA1C and lipid profile (TC, TG, HDL), LDL, VLDL and Non–HDL were calculated by computational methods. TG/HDLc ratio and Non HDLc/HDLc ratios were also calculated to assess cardiovascular risk.

Methodology:Biochemical & statistical analysis was done on all the selected 200 subjects. TG/HDL ratio and Non–HDLc/HDLc ratios were calculated.

Results: Total Cholesterol, TG, LDL & TG/HDLc ratio & Non–HDL/HDL ratio were found to be significantlyincreased in diabetics when compared with nondiabetics. HDL levels were found to be &slightly less in diabetics as compared to Nondiabetics.

Conclusion:We concluded that Non HDlc/HDLc ratio & TG/HDLc ratio can be used as early markers of cardiovascular risk.