Evaluation of antianxiety activity of lyophilized Aloe vera succulent in Albino Swiss mice

Dr. Rajesh Kumar; Dr. Massarat Jehan; Dr. Monika Sahu

Volume : IV, Issue : X, October - 2014

Evaluation of antianxiety activity of lyophilized Aloe vera succulent in Albino Swiss mice

Dr. Rajesh Kumar, Dr. Massarat Jehan, Dr. Monika Sahu

Abstract :

Anxiety disorders are quite common among the neuropsychiatric problems. Present pharmacological treatment is effective but not devoid of unwanted side effects. Aloe vera is a medicinal plant of great importance. In this study potential of Aloe vera succulent for antianxiety activity evaluated in Albino mice with Elevated plus maze and Light and Dark box models. It showed significant antianxiety activity in both models with 200mg/kg and 300mg/kg doses. The open arm and light box stay increased in dose dependant manner, while it was not significant with 100mg/kg dose.