Volume : III, Issue : VII, July - 2013
Erythroleukemia with Complex Cytogenetic Abnormalities: A case report with review of literature
Pooja K Suresh, Purnima S Rao, Urmila N Khadilkar
Abstract :
Acute Erythroleukemia (AEL) is a rare type of hematopoietic neoplasm, having a prevalence of 3–5% of all Acute Myeloid Leukemia (AML). We present a case report of acute erythroleukemia, a rare type of AML, with complex cytogenetic abnormalities. A 54–year old male presented with low grade fever and significant weight loss. Complete hemogram and a peripheral smear revealed pancytopenia with 18% blasts. It also showed features of hemolysis. Bone marrow (BM) study showed erythroid hyperplasia with erythroblasts constituting 85% of all nucleated cells and 21% myeloid blasts among non–erythroid cells. Flow cytometry revealed 23% blasts positive for CD33, CD34, CD117, CD36 and HLA–DR. Cytogenetic study revealed hypotetraploidy with numerous structural abnormalities indicating poor prognosis.
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DOI : 10.36106/ijar
Cite This Article:
Pooja K Suresh, Purnima S Rao, Urmila N Khadilkar Erythroleukemia with Complex Cytogenetic Abnormalities: A case report with review of literature Indian Journal of Applied Research, Vol.III, Issue.VII July 2013
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Pooja K Suresh, Purnima S Rao, Urmila N Khadilkar Erythroleukemia with Complex Cytogenetic Abnormalities: A case report with review of literature Indian Journal of Applied Research, Vol.III, Issue.VII July 2013
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