EFFICACY OF TRANSDERMAL BUPRENORPHINE PATCH 10 mg ON POSTOPERATIVE PAIN CONTROL IN PATIENTS UNDERGOING SPINE SURGERY

Manjula B P; Anand Mammen

Volume : IX, Issue : III, March - 2019

EFFICACY OF TRANSDERMAL BUPRENORPHINE PATCH 10 mg ON POSTOPERATIVE PAIN CONTROL IN PATIENTS UNDERGOING SPINE SURGERY

Manjula B P, Anand Mammen

Abstract :

Aim of this study is to evaluate the analgesic efficacy of transdermal buprenorphine patch 10 mg [10 µg/hr] in the management of acute post operative pain in patients undergoing elective spine surgery in terms of duration of post operative analgesia as the primary outcome. 60 patients aged 18– 55 yrs, posted for elective spine surgery, belonging to ASA class I and II were randomized into 2 equal groups, Group B and Group P. Transdermal Buprenorphine 10 mg patch was applied in Group B and Placebo patch was applied in Group P, 20 hrs before surgery. General anaesthesia was given to all patients. Post operatively Inj Diclofenac was administered as analgesic in both the groups. Inj.Tramadol was given as rescue analgesic whenever VAS >3. All patients were also monitored for drug related adverse effects and changes in hemodynamic status till post op day 5. Time to first post–operative rescue analgesic requirement was much delayed in Group B than in Group P [ 744.0 ± 8.64 min vs 61 ± 0.28 min, P<0.001 ]. We concluded that transdermal buprenorphine patch 10mg is effective in prolonging post–operative analgesia when applied 20 hrs before surgery.