Efficacy of Intra articular Sodium Hyaluronate and autologus Platelet Rich Plasma for management of pain in Osteoarthritis Knee

Dr Nimisha Verma

Volume : VIII, Issue : XII, December - 2018

Efficacy of Intra articular Sodium Hyaluronate and autologus Platelet Rich Plasma for management of pain in Osteoarthritis Knee

Dr Nimisha Verma

Abstract :

Osteoarthritis is a progressive, degenerative joint disorder resulting from the eakdown of articular cartilage. The platelets contain growth factors which have been shown to regulate articular cartilage metabolism. The present study aims to compare the efficacy of a single intra articular injection of autologus Platelet Rich Plasma with Sodium Hyaluronate injection in relieving pain in osteoarthritis knee patients and also assess the change in size of the cartilage by ultrasound imaging of the knee joint. A total of forty patients were included in the study. Pain relief was measured using Visual Analog Scale. Functional improvement was assessed using Oxford Knee score and Patient Satisfaction score. The articular cartilage thickness was assessed by ultrasound. Assessments were done at one, three and six months. Significant pain relief was observed in both the groups from their pre treatment levels at 1 month that persisted up to 6 months of the study period. Although the pain relief and satisfaction was better in patients receiving Intra Articular PRP, the difference in the size of the articular cartilage was not statistically significant in the two study groups.