Volume : VIII, Issue : IV, April - 2018
Cytological diagnosis of Pulmonary alveolar proteinosis from bronchoalveolar lavage specimen - A case report of silicoproteinotuberculosis and review of literature
Dr. Ajithakumari K, Dr. Radhika Pillai
Abstract :
We present a case report of unusual association of silicosis, pulmonary alveolar proteinosis and tuberculosis occurring in a 30 year old stone quarry worker exposed to sand dust since 15 years. Pulmonary alveolar proteinosis (PAP) is an uncommon disease in which there is progressive and inappropriate occupation of the lung alveoli by an excessive amount of unprocessed surfactant. Untill recently the gold standard for diagnosis of PAP was considered to be open lung biopsy followed by histopathological and ultrastructural examination.With the introduction of improved onchoscopic techniques, onchoalveolar lavage (BAL) is now employed as a useful diagnostic and therapeutic modality in the management of PAP. The cytological features of BAL fluid in PAP are unique and with supporting clinical and radiological evidences a confident diagnosis of PAP can be given so that the patient can be spared of a more invasive diagnostic procedure. The authors present a case report where a cytological diagnosis of PAP was made possible by routine Papanicolaou stained smears and PAS–D stains. The utility of BAL cytology in the diagnosis of PAP is discussed.The conclusion is that study of the onchoscopic lavage fluid is a useful diagnostic modality in PAP.
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DOI : 10.36106/ijar
Cite This Article:
Dr. Ajithakumari K, Dr.Radhika Pillai, Cytological diagnosis of Pulmonary alveolar proteinosis from bronchoalveolar lavage specimen‾A case report of silicoproteinotuberculosis and review of literature, INDIAN JOURNAL OF APPLIED RESEARCH : Volume-8 | Issue-4 | April-2018
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Dr. Ajithakumari K, Dr.Radhika Pillai, Cytological diagnosis of Pulmonary alveolar proteinosis from bronchoalveolar lavage specimen‾A case report of silicoproteinotuberculosis and review of literature, INDIAN JOURNAL OF APPLIED RESEARCH : Volume-8 | Issue-4 | April-2018
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