Comparative Evaluation of  Dengue ICT with Immunocapture Elisa in a tertiary care hospital.

Dr.P.Malini; Dr.T.Ravikumar; Dr.V.Vijayashree

Volume : VII, Issue : VII, July - 2017

Comparative Evaluation of Dengue ICT with Immunocapture Elisa in a tertiary care hospital.

Dr. P. Malini, Dr. T. Ravikumar, Dr. V. Vijayashree

Abstract :

Introduction: Dengue is considered as one of the world’s major emerging tropical diseases. Dengue is the second most common tropical disease next to Malaria.Specific IgM and IgG detection has been the mainstay of diagnosis for a long time. Aim and objectives: Comparative evaluation of ICT with Immunocapture ELISA in diagnosis of Dengue .Materials and methods:Blood was drawn from 350 suspected dengue cases and were subjected to both ICT and ELISA. Results: Out of 350 samples tested 107 were positive by ELISA (30.5%) and 92 by ICT (26.2%). Sensitivity, specificity, PPV and NPV of the ICT were calculated using MAC ELISA as reference. Conclusion: Immunocapture ELISA is more sensitive and reliable than ICT even though it is highly specific, rapid and easy to perform.