Clinico–epidemiological pattern of oral lesion in seropositive patients : a hospital base study

Volume : VIII, Issue : IX, September - 2018

Atin Halder, Ankit Halder, Saswati Halder, Medhatithi Barman, Koustabh Kumar

Background: Oral manifestations of HIV disease is important, as they affect the qualityof life

and usefulmarker of disease progression^.

Aims:Thestudy was designed to search for the oral lesions in seropositive patients and their

possibleprognostic value.

Methods: This prospective observational study included 211 new cases with

consecutive two ELISA test positive attended in OPD .Relevant investigations and

biopsies were taken to confirm clinical diagnosis . Thecausal relationship between

prevalence of oral lesions and demographical variants,therapeutic regimen and CD4

count were evaluated.The technique and protocol were approved by the ethics

committee of the institution.

Results :Out of 211 patients ,75 (35.44%) patients had detectable oral lesion with male

predominance .Majority belonged to the age group of 21– 30 years . All thevariants of

candidiasiswere seen. Pseudo memanous type was most frequentlyobserved .

Herpes simplex is the commonest viral infection. One case of hairy leukoplakia was

seen. Necrotizing ulcerative periodontitis (NUP) was observed in four cases.Aphthous

ulcer were seen in eight cases.

Conclusions :In our series cases with orofacial involvementhad CD4 count <600

cells/ml. Majorityof the patients had CD4< 200 cells/ml .