Volume : VIII, Issue : VI, June - 2018

Anti–aging and anti–wrinkle potential of Emblica officinalis

Chanchal Garg, Munish Garg

Abstract :

Aim: Present study is aimed to evaluate the anti–aging and anti–wrinkle potential of Emblica officinalis.

Method: The methanolic, ethyl acetate, n–butanol and aqueous extracts of Emblica officinalis were prepared and evaluated for its antioxidant, Hyaluronidase, MMP–1/collagenase and elastase inhibition activity.

Results: The IC₅₀ values of the methanolic, ethyl acetate, n–butanol and aqueous extracts of Emblica officinalis and ascorbic acid were found to be 33.04 μg/ml, 36.86 μg/ml, 38.39 μg/ml, 40.87 μg/ml and 29.25 μg/ml respectively. The IC₅₀ of hyaluronidase inhibition activity values of the methanolic, ethyl acetate, n–butanol and aqueous extracts of Emblica officinalis were 11.50 μg/ml, 51.39 μg/ml, 95.54 μg/ml, 137.63 μg/ml. The IC₅₀ values of the methanolic, ethyl acetate, n–butanol and aqueous extracts were found to be 14.40 μg/ml, 20.90 μg/ml, 37.46 μg/ml, 55.91 μg/ml respectively. The IC₅₀ values of MMP–1/collagenase inhibitory activity of the methanolic, ethyl acetate, n–butanol and aqueous extracts of Emblica officinalis were found to be 25.52 μg/ml, 37.83 μg/ml, 46.75 μg/ml, 58.49 μg/ml and standard catechin was 5.96 μg/ml.

Conclusion: The present study revealed that Emblica officinalis may serve as a potent antiaging agent. Among the test samples, Emblica officinalis methanolic extract showed the most potent antioxidant as well as enzymatic inhibition while aqueous extract showed the least antioxidant as well as enzymatic inhibition. 

Keywords :

Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Chanchal Garg, Munish Garg, Anti–aging and anti–wrinkle potential of Emblica officinalis, INDIAN JOURNAL OF APPLIED RESEARCH : Volume-8 | Issue-6 | June-2018

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