Volume : VIII, Issue : II, February - 2018
AN OBSERVATIONAL STUDY TO COMPARE LOW DOSE ESMOLOL AND LOW DOSE LABETALOL FOR ATTENUATION OF SYMPATHOMIMETIC RESPONSE TO LARYNGOSCOPY AND INTUBATION
Singla Priyanka R. , Chauhan Dinesh
Abstract :
Laryngoscopy and endotracheal intubation are associated with cardiovascular & neurological changes. Studies compå esmolol with labetalol to attenuate pressor response are lacking.
AIM:
To compare the effects of low doses of esmolol and labetalol for attenuation of sympathomimetic response to laryngoscopy and intubation.
METHODS:
Study Design: Observational study
Study Site: Dhiraj Hospital,Piparia
Study Duration: 1year
Study Population: After ethical committee’s approval, this study was carried out on 60 patients, randomly and equally allocated to any of the two groups using chit method.
HR,SBP,DBP,MAP,RPP&ECG changes were recorded prior to induction, at–intubation and 1,3,5&10min post–intubation.
RESULTS:
Analysis showed no significant variation in HR,SBP&DBP at intubation for both the studied drugs but post–intubation analysis revealed lower HR,SBP,MAP&RPP in labetalol group(p<0.001).
CONCLUSION(s) :
The measurement of baseline and postintubation parameters revealed statistically significant variation in HR,SBP,MAP&RPP in Esmolol as compared to Labetalol thus proving our study.
Keywords :
Article:
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DOI : 10.36106/ijar
Cite This Article:
Singla Priyanka R., Chauhan Dinesh, AN OBSERVATIONAL STUDY TO COMPARE LOW DOSE ESMOLOL AND LOW DOSE LABETALOL FOR ATTENUATION OF SYMPATHOMIMETIC RESPONSE TO LARYNGOSCOPY AND INTUBATION, INDIAN JOURNAL OF APPLIED RESEARCH : Volume-8 | Issue-2 | February-2018
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Singla Priyanka R., Chauhan Dinesh, AN OBSERVATIONAL STUDY TO COMPARE LOW DOSE ESMOLOL AND LOW DOSE LABETALOL FOR ATTENUATION OF SYMPATHOMIMETIC RESPONSE TO LARYNGOSCOPY AND INTUBATION, INDIAN JOURNAL OF APPLIED RESEARCH : Volume-8 | Issue-2 | February-2018
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