Volume : VIII, Issue : V, May - 2018
A study of thyroid abnormalities in first episode and recurrent depressive disorder
Dr. Manish Borasi, Dr. Hemika Agrawal, Dr. Nimesh G Desai, Dr. Vijender Singh, Dr. Neelam Chhillar
Abstract :
Introduction: Depression is one of the leading causes of disease worldwide. Depression is not only a common, often
chronic, and recurrent disorder, but it is cardinally associated with signicant impairment in work and daily social and
psychological well–being. Depression is projected to be the second leading cause of disease burden for both men and women across age groups
by the year 2020. A key variable inuencing rates of recovery, relapse, and recurrence is the presence of medical or psychiatric comorbid
illnesses. Among medical co–morbid illness, thyroid abnormalities are very common. Both excess and insufcient thyroid hormones can cause
mood abnormalities including depression that is generally reversible with adequate thyroid treatment.
Materials and method: The study was carried out over a period of 9 months on patients registered in psychiatry clinic at tertiary neuropsychiatry
center suffering from depressive disorder as per the ICD–10(DCR). Then after applying inclusion and exclusion criteria and explaining the
purpose of study, those patients who give consent were included. Severity of depression will be rated using HAM–D. Thyroid prole of those
patients who gave consent were done in laboratory of neurochemistry department. The results thus generated were subjected to appropriate
statistical analysis.
Results and conclusion: Our study reveals that 12% of the subjects had decreased T3 levels, 36% subjects were found to have increased TSH
levels . Subclinical and clinical hypothyroidism were seen in 35% of subjects with depressive disorder.The occurrence of subclinical
hypothyroidism was more common in RDD (25.9%) in comparison to rst episode (19.6%).
Keywords :
Article:
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DOI : 10.36106/ijar
Cite This Article:
Dr. Manish Borasi, Dr. Hemika Agrawal, Dr. Nimesh G Desai, Dr. Vijender Singh, Dr. Neelam Chhillar, A study of thyroid abnormalities in first episode and recurrent depressive disorder, INDIAN JOURNAL OF APPLIED RESEARCH : Volume-8 | Issue-5 | May-2018
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Dr. Manish Borasi, Dr. Hemika Agrawal, Dr. Nimesh G Desai, Dr. Vijender Singh, Dr. Neelam Chhillar, A study of thyroid abnormalities in first episode and recurrent depressive disorder, INDIAN JOURNAL OF APPLIED RESEARCH : Volume-8 | Issue-5 | May-2018
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