A study of maintenance and emergence characteristics of Inhalational Anaesthetic Agents

Dr. Vaishali C. Shelgaonkar; Dr. Medha A Sangawar; Dr. Anant B. Puri; Dr. Sachin M. Hiradeve

Volume : X, Issue : IV, April - 2020

A study of maintenance and emergence characteristics of Inhalational Anaesthetic Agents

Dr. Vaishali C. Shelgaonkar, Dr. Medha A Sangawar, Dr. Anant B. Puri, Dr. Sachin M. Hiradeve

Abstract :

Background: Inhaled anesthetics allow rapid emergence from anesthesia because of easy titrability with inherent neuromuscular blocking effects that make them more suitable for day care anesthesia too. Aim of this study was to assess the maintenance and emergence characteristics of isoflurane, sevoflurane or desflurane in adult patients undergoing laparoscopic surgical procedures. Methods: The study enrolled total 105 adult patients of either sex, ASA grade I or II, aged between 18–60 years.They were randomly allocated in three equal groups, Group I patients received isoflurane, group S received sevoflurane and group D received desflurane as inhalational agent. The various study parameters, side effects and complications were recorded. Results: Overall mean dial settings required (%) were in group I was 1.09+/–0.32, in group S was 1.58+/–0.36, and in group D was 3.82+/–0.62. Mean MAC value was lower in group I as compared group S and group D, (P ˃0.05) while mean BIS was found to be within range of 40 to 60 in all three groups; being lowest in group I, as against group S and group D, (P <0.05).All the three agents provided almost similar (statistically insignificant difference) intraoperative hemodynamic variation, but best stability with Sevoflurane. The early and intermediate recovery time was shorter in group D than group S than group I.Study was devoid of any major side effects and complications except PONV in some patients of group S and D. Conclusion: From the result of present study, we conclude that all three volatile agents were practically safe and useful for laparoscopic surgical procedures, Desflurane being marginally superior.