A STUDY OF EPITHELIAL CHANGES IN ADJOINING AREAS IN MODIFIED RADICAL MASTECTOMY SPECIMENS  IN CASES OF INFILTRATING DUCT CARCINOMA BREAST

Devika Gupta; Pooja Gupta; Satish Mendonca; Shilajeet Bhattacharya

Volume : VII, Issue : III, March - 2017

A STUDY OF EPITHELIAL CHANGES IN ADJOINING AREAS IN MODIFIED RADICAL MASTECTOMY SPECIMENS IN CASES OF INFILTRATING DUCT CARCINOMA BREAST

Devika Gupta, Pooja Gupta, Satish Mendonca, Shilajeet Bhattacharya

Abstract :

Aim of the Study: The aims and objectives of our research paper was to detect the incidence of epithelial proliferations in adjoining uninvolved east in Infiltrating Duct Carcinoma(IDC) cases for which Modified Radical mastectomy was done. Material and Methods: The study involved analysis of 102 Modified Radical Mastectomy (MRM) specimens of Infiltrating Duct Carcinoma over a period of 18 months Results: .The epithelial lesions and the tumor were identified based on morphological criteria and tumor was graded as per Nottingham modification of the Bloom Richardson system. Statistical analysis involved Correlation if any between the tumor parameters and epithelial lesions which was determined using Pearsons Chi square test (p < 0.05; significant). Conclusion: It is recommended that extensive random sampling be done from unaffected quadrants which will make surgical pathologists aware of premalignant changes existing and their evolution into east cancer.