A Study of clinical and hormonal evaluation of hypothalamo pituitary dysfunction after traumatic brain injury and subarachnoid hemorrhage

Mounika Guntaka; Babulreddy Hanmayyagari; Manoj Gopinath Mengade; Arun Mukka

Volume : X, Issue : V, May - 2020

A Study of clinical and hormonal evaluation of hypothalamo pituitary dysfunction after traumatic brain injury and subarachnoid hemorrhage

Mounika Guntaka, Babulreddy Hanmayyagari, Manoj Gopinath Mengade, Arun Mukka

Abstract :

Hypopituitarism is one of the common complication following traumatic ain injury or aneurysmal subarachnoid hemorrhage and potentially can contribute to morbidity and poor recovery after ain injury. Materials and methods: Our study included 15 patients following TBI or SAH in whom hormonal evaluation was performed at baseline, 3 months, 6 months following the injury. Study also attempted correlation of hormonal values with that of clinical scoring (GCS), and with radiological findings (CT/MRI). At baseline, 7 out of 15 patients had evidence of hormonal derangement. Results: Pituitary dysfunction persisted in 4 patients at the end of 6 months from baseline. Hypocortisolism was the most common disorder at the baseline where as GHD was the most common at 6 months. Conclusion: Evaluation of intactness of hypothalamo–pituitary axis is of paramount clinical importance in subjects following TBI & SAH at baseline and in the followup, as hormonal derangements are common and correcting the same can improve the clinical outcomes.