A PROSPECTIVE STUDY ON COMPARISON OF URINARY CYTOLOGY WITH HISTOPATHOLOGICAL EXAMINATION IN BLADDER TRANSITIONAL CELL CARCINOMA

Dr.Vijayakumar P.; Dr. Gnanasekaran T.

Volume : IX, Issue : III, March - 2019

A PROSPECTIVE STUDY ON COMPARISON OF URINARY CYTOLOGY WITH HISTOPATHOLOGICAL EXAMINATION IN BLADDER TRANSITIONAL CELL CARCINOMA

Dr. Vijayakumar P. , Dr. Gnanasekaran T.

Abstract :

Introduction : Bladder cancer accounts for 7% of all cancers in male and 2% of all cancers in female. Urinary cytology has prominent role in the multidisciplinary diagnostic approach to bladder cancer. It is used as a valuable adjunct to cystoscopy and biopsy for diagnosis and follow up of patients with bladder cancer. Urine cytology remains gold standard for bladder cancer screening. It has high specificity but low sensitivity for both high–grade and low–grade tumors. Materials and Methods:A prospective study conducted from 2016–2018. Inclusion criteria was patients with carcinoma of bladder diagnosed radiologically. Urine cytology was done in all cases preoperatively and correlated with histopathology post operatively. Results : In our Prospective study, 70 patients were included those who are presented with LUTS due to Bladder TCC detected by ultrasound. Age of patient ranged from 40 to 89 .68 cases were confirmed histologically, of which 24 cases of low grade TCC, 44 cases of High grade TCC, only 2 cases are histologically negative. Out of 68 cases of histologically proved TCC, 52 cases were correctly diagnosed by urine cytological examination. histological confirmed TCC occur in 68 patients on which patients 76% were diagnosed cytologically Conclusions: Cytology still considered a useful tool in the diagnosis and follow–up of Ca bladder (TCC) with a good sensitivity and high specificity