A Comparative Study of in Hospital Outcome of Patients with ST-Segment Elevation Myocardial Infarction with and Without Diabetes Mellitus, after Thrombolytic Therapy in a Tertiary Care Centre in Eastern Bihar.

Dr Ravi Anand; Dr Hemshankar Sharma

Volume : IX, Issue : III, March - 2019

A Comparative Study of in Hospital Outcome of Patients with ST-Segment Elevation Myocardial Infarction with and Without Diabetes Mellitus, after Thrombolytic Therapy in a Tertiary Care Centre in Eastern Bihar.

Dr Ravi Anand, Dr Hemshankar Sharma

Abstract :

Introduction: Diabetes mellitus is considered as a major health problem and an epidemic throughout the world. The mortality of patients with diabetes is almost twice that of non–diabetic. The outcome of in–hospital patients with myocardial infarction with and without diabetes after thrombolytic therapy is presented here. Aims and Objectives: To compare the outcome of patients with myocardial infarction after thrombolysis in diabetics and non–diabetics in patients of Medicine Department of Jawahar Lal Nehru Medical College and Hospital, Bhagalpur, Bihar. Material and Methods: A retrospective, observational study was carried out at Medicine Department of Jawahar Lal Nehru Medical College and Hospital, Bhagalpur, Bihar between the period of October 2016 to September 2018. Patients who presented with acute myocardial infarction having ST–elevation as MI picture, were treated with streptokinase as a thrombolytic agent. Baseline ECG was taken on admission and the one after 60 minutes of thrombolysis. The study group involved two types: (i) diabetic (ii) nondiabetics. Results: A total of 790 patients were included in the present study. Out of them around 208 were females and 582 were males. ST–segment resolution in non–diabetic patients was found in 360 patients out of 372 and in diabetics it was found in 348 patients out of 416. Complications related to post fiinolytic therapy was more prevalent in diabetics 296 patients (71.15%) as compared to those in non–diabetics 94 patients (25.26%). Mortality was observed only with diabetics (23.52%) as compared to no mortality in non–diabetics. Conclusion: Overall, morbidity and mortality of diabetic patients with Acute Myocardial Infarction was found to be greater as compared to non–diabetics, post thrombolysis.