A CASE OF PULMONARY LANGERHANS CELL HISTIOCYTOSIS IN A NON–SMOKER FEMALE

Dr. Darshan Pandya; Dr. Vishal Parmar; Dr. Dhaval Chaudhary

Volume : IX, Issue : IX, September - 2019

A CASE OF PULMONARY LANGERHANS CELL HISTIOCYTOSIS IN A NON–SMOKER FEMALE

Dr. Darshan Pandya, Dr. Vishal Parmar, Dr. Dhaval Chaudhary

Abstract :

Langerhans cell histiocytosis (LCH) is a rare disorder caused by monoclonal Langerhans cells proliferation in bone, skin, lung, lymph nodes, liver, spleen, nervous or hematopoietic system.Pulmonary LCH is proliferation of monoclonal Langerhans cells in lung interstitium and airspaces. Etiology is unknown, but cigarette smoking plays an important role. Symptoms are dyspnea, cough, fatigue, and pleuritic chest pain. Diagnosis is based on history and imaging tests and sometimes on onchoalveolar lavage and biopsy findings. Corticosteroids are given in many cases, but efficacy is unknown. Lung transplantation is usually curative when combined with smoking cessation.