TWO YEAR RETROSPECTIVE STUDY OF COMBINATION OF MIFEPRISTONE AND MISOPROSTOL -AN EFFECTIVE METHOD OF MEDICAL ABORTION UPTO GESTATIONAL AGE OF 49 DAYS.

Dr.Seema C.Kshirsagar; Dr. Uma N Wankhede

Volume : VI, Issue : VIII, August - 2017

TWO YEAR RETROSPECTIVE STUDY OF COMBINATION OF MIFEPRISTONE AND MISOPROSTOL -AN EFFECTIVE METHOD OF MEDICAL ABORTION UPTO GESTATIONAL AGE OF 49 DAYS.

Dr. Seema C. Kshirsagar, Dr. Uma N Wankhede

Abstract :

INTRODUCTION: A combination of antiprogesterone mifepristone and prostaglandin analogue misoprostol provides an effective medical method for termination of pregnancy up to gestational age of 49 days.

OBJECTIVE: To assess the efficacy of this medical regimen for termination of pregnancy up to 49 days of pregnancy.

METHOD: A hospital based retrospective observational study was carried out in department of obstetrics and gynaecology in Sassoon General Hospital Pune for a period of two year where 58 women requesting for medical abortion were studied. The medical regimen used was mifepristone 200 mg orally followed 48 hours later by misoprostol 800 microgram administered in posterior vaginal fornix .

RESULTS: The overall success rate of this regimen was 91.4%. Where success was defined as achieving complete abortion without needing surgical evacuation. Surgical evacuation was needed in 5(8.6%) patients i.e. for incomplete abortion .

CONCLUSION: combination of oral mifepristone 200mg followed 48 hours later by vaginal misoprostol 800mcg is an effective method of medical termination of pregnancy.