Volume : VIII, Issue : IV, April - 2019

TOTAL AND DIFFERENTIAL LEUCOCYTE COUNT IN CASES OF HYPERTENSION

Dr Nilam Patel, Dr Pragna P Sharma

Abstract :

BACKGROUND : Low grade inô€ƒ¸ammation localized in vascular tissue is increasingly recognized as an important contributor to the pathophysiology of hypertension, to the initiation and progression of atherosclerosis and the development of cardiovascular disease (CVD). Accumulating evidence suggests that systemic inô€ƒ¸ammation and endothelial activation underlie the development of hypertension. Leukocytes have the potential to contribute in number of ways to the arterial hypertension per se. Each of these possibilities requires further investigation in hypertension. OBJECTIVES : The study was conducted with a view to ô€ƒ¶nd any signiô€ƒ¶cant increase in total and differential leukocyte count in known cases of hypertensive patients in Indian population. MATERIAL AND METHODS: 50 hypertensive patients of age 34-78 years, out of which 25 males and 25 females, were recruited from the outpatients department of medicine, V.S. Hospital from the year 1-12-2013 to 30-11-2015.Patients who were willing to participate in the study were included. Hypertension was deô€ƒ¶ned as systolic BP ≥ 140mmHg or diastolic BP ≥90 mmHg. or history of taking antihypertensicve medicine. 2 ml of blood was drawn into EDTA containing vials from such patients. Two separate counts were performed by AUTOMATED HEMATOLOGY ANALYSER. RESULTS: The mean total leucocyte count for the study group as compared to the controls were 8087.28±445.093 cells/cumm and 5853.54±862.750 cells/cumm respectively which was statistically signiô€ƒ¶cant. The mean percentage neutrophils were 64.76±5.370 for study group and 53.42±4.146 for the controls.Mean percentage neutrophils showed statistically signiô€ƒ¶cant difference. CONCLUSION : In this study, total leucocyte count and neutrophil count of hypertensive group, although in normal range, were signiô€ƒ¶cantly higher than controls indicating that inô€ƒ¸ammation is ongoing.

Keywords :

Article: Download PDF    DOI : https://www.doi.org/10.36106/gjra  

Cite This Article:

TOTAL AND DIFFERENTIAL LEUCOCYTE COUNT IN CASES OF HYPERTENSION, Dr Nilam Patel, Dr Pragna P Sharma GLOBAL JOURNAL FOR RESEARCH ANALYSIS : Volume-8 | Issue-4 | April-2019

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