To study differences in bacteriological profile in sputum sample of smoker and non-smoker patients of Acute Exacerbation of Chronic Obstrucive Pulmonary Diseases (AECOPD)

Dr. Soniya Saxena; Dr. Nishant Srivastava; Dr Vijay Kumar Ramnani; Dr Lokendra Dave

Volume : VII, Issue : IV, April - 2018

To study differences in bacteriological profile in sputum sample of smoker and non-smoker patients of Acute Exacerbation of Chronic Obstrucive Pulmonary Diseases (AECOPD)

Dr. Soniya Saxena, Dr. Nishant Srivastava, Dr Vijay Kumar Ramnani, Dr Lokendra Dave

Abstract :

Introduction- COPD is a leading cause of worldwide mortality and disability. Almost all forms of smoking products such as cigarettes and bidies used in different states were found to be associated with COPD. In non-smokers, especially women, exposures to indoor air pollution from domestic combustion of solid fuels is an important factor. Aim- To study differences in bacteriological profile in sputum sample of smoker and non-smoker patients of (AECOPD). Material and Methods-200 clinically diagnosed cases of AECOPD of age ≥45 years were recruited. Their sputum samples each were processed by conventional methods. Preparation of media, reagents, Gram staining, identification of culture isolates, different tests, including antibiotic sensitivity tests were carried out following standard laboratory methods.Results- In our study Gram negative bacilli were predominant in smoker COPD cases, as Gram positive cocci and Gram negative bacilli were isolated in 23 and 9 cases respectively in smokers and non-smoker COPD cases. Only Gram positive cocci were isolated in all nine cases. There was no gram negative organism isolated in non smoker COPD group. Conclusion- Gram negative bacilli were predominant in smoker COPD cases ,where as Gram positive organisms were predominant in non-smoker COPD population.