To study and compare recovery characteristics and post extubation adverse events of sevoflurane with halothane for inhalational anaesthesia in paediatric patients.

Dr Aditi Jain; Dr Tahir Ali Khan; Dr Aditya Agarwal

Volume : VII, Issue : II, February - 2018

To study and compare recovery characteristics and post extubation adverse events of sevoflurane with halothane for inhalational anaesthesia in paediatric patients.

Dr Aditi Jain, Dr Tahir Ali Khan, Dr Aditya Agarwal

Abstract :

When it comes to inhalational anaesthesia in paediatric patients, Sevoflurane , with its non pungent odour, low blood – gas solubility, cardiostable properties and minimal hepatotoxicity takes the advantage over halothane but recovery after sevoflurane anaesthesia is, however associated with a high incidence of agitation and delirium. We designed this study to compare the recovery characteristics and post extubation adverse events of sevoflurane with halothane anaesthesia in children aged 2 – 10 years undergoing various commonly performed surgical procedures. Sixty patients, aged between 2 to 10 years undergoing various surgeries were randomly divided into two groups of 30 each to receive either sevoflurane or halothane anaesthesia, induced by using equipotent incremental doses of either of the inhalational agent upto 3 MAC. Anaesthesia was then maintained with either of the inhalational agents at 0.5 MAC with nitrous oxide (60%) in oxygen (40%). At the end of surgery, extubation characteristics and steward recovery score were assessed and compared. Our study showed a significantly high incidence of postoperative excitement and restlessness during recovery from sevoflurane anaesthesia compared to halothane( 43% vs 3.33%) with significantly better steward recovery score at 3 min (25/30 patients in sevoflurane group vs 11/30 patients in halothane group ).