Synthesis, characterization and antibacterial activity of Zn (II) tetraaza macrocyclic complexes

Preeti Jain; Vandna Singh; Rajni Singh

Volume : V, Issue : IX, September - 2016

Synthesis, characterization and antibacterial activity of Zn (II) tetraaza macrocyclic complexes

Preeti Jain, Vandna Singh, Rajni Singh

Abstract :

The objective of present study was to synthesize a new series of metal based therapeutic agents with good antimicrobial and antioxidant properties and their structural characterization. Synthesis of Zn complexes of type[M(C16 H10N4O2) X2], where M=Zn(II), X = Cl-, NO3- and CH3COO- derived from template condensation of 1,3-dicarbonyl-phenyldihydrazide and 1H-indole-2,3-dione(isatin) and their characterization by UV-Vis, FT-IR,H-NMR and mass spectral studies. Antimicrobial activity was determined by using agar well diffusion method against two bacterial strains S.aureus and B.Subtilis. All test compounds posses varied but significant antibacterial activity against the bacterial strains