Study on Prevalence of Dengue fever in a tertiary care Hospital, South India

Swarna.S; Lallitha.S; Amuthan.M; Ganesan. M; Rajkumar.M; Dhanasezhian.A; Sekhar.R; K.M.Mythreyee

Volume : VII, Issue : I, January - 2018

Study on Prevalence of Dengue fever in a tertiary care Hospital, South India

Swarna. S, Lallitha. S, Amuthan. M, Ganesan. M, Rajkumar. M, Dhanasezhian. A, Sekhar. R, K. M. Mythreyee

Abstract :

BACKGROUND:

Dengue is an acute feile arboviral illness affecting the tropical and sub tropical regions of the world. It is one of the most important causes of morbidity and mortality in India. This study was done to find out the prevalence of dengue virus infection and its serotype in and around Theni District.

METHODS:

The study was conducted at Government Theni Medical College (GTMC), Theni, during January 2015 to July 2017. Patients with symptoms of dengue fever attending GTMC hospital were included for the study. Serum samples were tested for dengue NS1 antigen and IgM antibodies by ELISA. Out of 1292 samples, 989 were tested for IgM and 303 were tested for NS1 antigen detection. The NS1 positive samples were further subjected to Real Time PCR for the identification of dengue serotypes.

Results:

Dengue infection was confirmed in 520 (40.25%) cases which include 383 IgM positives and 137 NS1 positives. Paediatric patients were found to be the predominant 390 (75%)] propotion among the dengue cases, whereas adults accounts for only 130(25%)., Circulation of all four dengue serotypes were detected in our region with predominance of serotype 1.

Conclusion:

Dengue infection in our region is documented throughout the year which requires the strengthening of mosquito control program to contain the risk of epidemic during rainy season.